The top two seeds square off in the AFC Championship Game and while Patrick Mahomes has the better history it is hard to go past Baltimore as being the best team in the conference.
The San Francisco 49ers finished the season with the best record and are clear favourites to win the Super Bowl but they will not get it all their own way when Green Bay head to Santa Clara.
Baltimore finished with the No.1 seed in the AFC but they will not get a cakewalk when they host rookie sensation CJ Stroud and his Houston Texans.
The Chiefs and Bills meet in the playoffs for the third time in four years, with Buffalo hosting for the first time.
Detroit broke a thirty year plus playoff win drought last week and will be desperate to make it two straight against the plucky Bucs.
The Eagles go in as road favourites despite having just a single win from their last six regular season games.
Detroit are favoured in a playoff game for just the fourth time since 1960 but look there for the taking against the plucky LA Rams and their former QB Matt Stafford.
Dallas ended up unlikely winners of the NFC East and host wild card team Green Bay in what is a massive boon for rookie starter QB Jordan Love.
The Buffalo Bills are the biggest favourites of Wildcard Weekend when they host a Pittsburgh Steelers team without star defensive end TJ Watt.
The final week of the regular season kicks off with the Steelers hosting the Ravens, after which the Colts play the Texans with a playoff spot on the line.